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Critical Limitations Missing Pharmacokinetic Data: The researchers did not measure actual GHK-Cu concentrations in the brain

Forrester MT, Benhar M, Stamler JS (2006) Nitrosative stress in ER: a new role for S-nitrosylation in neurodegenerative diseases

The above is summarized in the following graph: Adrenal Exhaustion While Stage 1 (flight or fight response) and Stage 2 (organ resistance) of Adrenal Fatigue have been studied from a patho-physiological perspective for some decades, our clinical understanding of the myriad of symptoms and their convoluted presentations in Stage 3 (Adrenal Exhaustion) is still in its infancy at best

Where the consumer-facing market routinely undersells what the literature supports (for example, the breadth of GHK-Cu gene-expression effects), we have followed the literature rather than the marketing

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